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Gout Metabolomics Service

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Gout Metabolomics Service

Gout-like diseases (disorders of purine metabolism, hyperuricemia, gouty arthritis and gouty nephropathy) are a group of metabolic diseases with increasing prevalence and recurrence year by year, mainly related to disorders of purine metabolism and/or imbalance of uric acid metabolism. Hyperuricemia develops when excessive purines are metabolized into uric acid or uric acid excretion is reduced due to factors such as genetic mutations or pathological damage. Further development of gout-related disease occurs when excess urate crystals are deposited in joint cavities, joint capsules, kidneys, etc.

The exact pathogenesis of gout is not yet fully understood. Finding precise biomarkers, exploring pathogenesis and tapping targets to develop new drugs are the focus of gout research.

Given that metabolic profiles are unique to each individual, fluctuations and differences in metabolite levels can indirectly reflect the state of the organism and the underlying mechanisms of the disease. Creative Proteomics provides gout metabolomics solutions to help identify precise bio-diagnostic markers, explore pathogenesis, and develop new drugs on target.

Gout Diseases Metabolomics Solutions

01

Studies related to purine metabolism

Purines are closely associated with the development of hyperuricemia, gout, and kidney disease.

Purine diet study

Purine content assay

02

Metabolomic analysis of hyperuricemia

Uric acid content determination

Biomarker discovery for hyperuricemia

Anti-hyperuricemia drug mechanism of action study

03

Metabolomic analysis of gout-related diseases

Gout marker discovery

Anti-gout drug mechanism study

Metabolomics Analysis Process for Gout

Gout Metabolomics Service

Technology Platform for Metabolomics Analysis

Multiple analytical platforms, including GC-MS, LC-MS, UPLC-MS. Thousands of metabolites can be screened from a single biological sample, providing a comprehensive approach for probing disease mechanisms.

ChromatographyMass Spectrometry
GC (Q Exactive) (- mode MS)
HPLC: HILIC (+/- mode MS)
HPLC: RP C18 (+/-mode MS)
IC (- mode MS)
Q Exactive MS
Orbitrap Tribrid MS

Creative Proteomics is a well-established partner in biopharmaceutical research and has extensive experience in metabolomics analysis. We provide solutions for gout diseases in the direction of metabolomics analysis, accelerating the exploration of new horizons in science. If you want to know more, please contact us. Looking forward to cooperating with you.

For Research Use Only. Not for use in diagnostic procedures.

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