Gout Metabolomics Service
Gout-like diseases (disorders of purine metabolism, hyperuricemia, gouty arthritis and gouty nephropathy) are a group of metabolic diseases with increasing prevalence and recurrence year by year, mainly related to disorders of purine metabolism and/or imbalance of uric acid metabolism. Hyperuricemia develops when excessive purines are metabolized into uric acid or uric acid excretion is reduced due to factors such as genetic mutations or pathological damage. Further development of gout-related disease occurs when excess urate crystals are deposited in joint cavities, joint capsules, kidneys, etc.
The exact pathogenesis of gout is not yet fully understood. Finding precise biomarkers, exploring pathogenesis and tapping targets to develop new drugs are the focus of gout research.
Given that metabolic profiles are unique to each individual, fluctuations and differences in metabolite levels can indirectly reflect the state of the organism and the underlying mechanisms of the disease. Creative Proteomics provides gout metabolomics solutions to help identify precise bio-diagnostic markers, explore pathogenesis, and develop new drugs on target.
Gout Diseases Metabolomics Solutions
Studies related to purine metabolism
●Purines are closely associated with the development of hyperuricemia, gout, and kidney disease.
●Purine diet study
●Purine content assay
Metabolomic analysis of hyperuricemia
●Uric acid content determination
●Biomarker discovery for hyperuricemia
●Anti-hyperuricemia drug mechanism of action study
Metabolomic analysis of gout-related diseases
●Gout marker discovery
●Anti-gout drug mechanism study
Metabolomics Analysis Process for Gout
Technology Platform for Metabolomics Analysis
Multiple analytical platforms, including GC-MS, LC-MS, UPLC-MS. Thousands of metabolites can be screened from a single biological sample, providing a comprehensive approach for probing disease mechanisms.
|GC (Q Exactive) (- mode MS)|
HPLC: HILIC (+/- mode MS)
HPLC: RP C18 (+/-mode MS)
IC (- mode MS)
|Q Exactive MS|
Orbitrap Tribrid MS
Creative Proteomics is a well-established partner in biopharmaceutical research and has extensive experience in metabolomics analysis. We provide solutions for gout diseases in the direction of metabolomics analysis, accelerating the exploration of new horizons in science. If you want to know more, please contact us. Looking forward to cooperating with you.
For Research Use Only. Not for use in diagnostic procedures.