Overview
Lipids are hydrophobic or amphipathic small molecules which include fats, waxes, sterols, fat-soluble vitamins (such as vitamins A, D, E and K), monoglycerides, diglycerides and phospholipids. The important roles of lipids in biological physiology are evident not only in energy storage and structural components of cellular membranes, but also in signal transduction, membrane trafficking and morphogenesis. Lipid metabolism is the synthesis and degradation of lipids in cells, consisting of the breakdown or storage of fats for energy and the synthesis of structural and functional lipids like those involved in the construction of cell membranes. The majority of lipids found in animals from ingesting food are triglycerides and cholesterol. Other types of lipids found in the body are fatty acids and membrane lipids. Since its essential roles in animals, any process that fundamentally interrupts the generation of lipids leads to serious diseases like cardiovascular diseases and osteoporosis. In Creative Proteomics, we provide reliable, rapid and cost-effective inositol phosphate analysis service to speed up your research aims ranging from diseases diagnosis to gaining new insights in disease mechanism or treatment.
The Main Applications of Lipid Metabolism Service
Identifying novel biomarkers of diseases
Improving diagnose diseases
Accelerating development of novel drugs
Gaining new mechanism of diseases
Advantages of Our Lipid Metabolism Service
Constantly optimized protocol and analytical software
Professional experiment design
Quick turnaround time
High accuracy, specificity, and sensitivity
Service Workflow
Creative Proteomics offers lipid metabolism analysis service in a reliable and effective manner, based on our cutting-edge high-performance liquid chromatography (HPLC) platforms. The experimental procedures contain four main procedures: sample collection, metabolites extraction, HPLC data analysis and bioinformatics analysis (Figure 1). Our service will be tailored to specific samples and needs for optimal results.
Figure 1. The overall workflow of lipid metabolism service.
The Potential Detectable Lipid Metabolism Related Metabolites at Creative Proteomics
Sample Requirements
We can analyze a wide range of biological materials including but not limited to cells and solid tissues from humans and animals, such as mice, rats, rabbits. If you need transport your samples to us, please follow the below requirements for different kinds of sample:
- Blood/plasma: 500ul/sample
- Urine: 1ml/sample
- Tissue: 200mg/sample
- Cells: 1x107/sample
- Feces: 500mg/sample
- Shipment condition: dry ice
Report Delivery
- Experimental protocols
- Instrumental factors of HPLC
- The raw data files of HPLC and the summary of HPLC data quality
- Bioinformatics analysis report
Based on advanced HPLC platforms for the determination of lipid metabolism, professional bioinformatic analysis software and experienced technicians and scientists, Creative Proteomics provides customer-tailored lipid metabolism analysis service with rapid experimental procedures and easy to read report, to accelerate your scientific research.
References
- Nordestgaard BG, Chapman MJ, Ray K, et al. Lipoprotein(a) as a cardiovascular risk factor: current status. Eur Heart J 2010;31: 2844–2853.
- Tian Li, Yu Xijie. Lipid metabolism disorders and bone dysfunction--interrelated and mutually regulated. Mol Med Rep. 2015.12:783-794.
For Research Use Only. Not for use in diagnostic procedures.