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Respiratory Diseases Metabolomics Service

Respiratory diseases are closely related to metabolism, involving calcium metabolism, glycolysis, lipid metabolism, metabolic reprogramming, and flora metabolism. Metabolic abnormalities are closely linked to the development of respiratory diseases.

Metabolomic data can improve the understanding of disease development mechanism, discover novel markers for more accurate clinical prevention and diagnosis, and also identify new targets for treatment. Therefore, metabolomics is increasingly used in the study of bronchial asthma, chronic obstructive pulmonary disease, cystic fibrosis, acute respiratory distress syndrome, tuberculosis, lung cancer, and other respiratory diseases.

Creative Proteomics analyzes endogenous small molecule metabolites through high-throughput, high-resolution and high-sensitivity metabolomics methods and mass spectrometry to find specific biomarkers and analyze their metabolic pathways, helping to reveal the mechanism of action of metabolites in various life activities.

Respiratory Diseases Metabolomics Solutions

Metabolomic analysis of asthma

Analysis of potential asthma biomarkers. Analysis of metabolic differences between asthma model and control groups. Analysis of representative metabolic patterns of asthma in different settings.

Metabolomic analysis of chronic obstructive pulmonary disease (COPD)

Analysis of differences in plasma and urine small molecule metabolite profiles between COPD patients and healthy populations.

Metabolomic analysis of cystic fibrosis (CF)

Search for potential biomarkers of cystic fibrosis.

Metabolomic analysis of pulmonary tuberculosis

Analysis of potential tuberculosis biomarkers. Analysis of metabolic differences between Mycobacterium tuberculosis infection model and control group.

Metabolomic analysis of lung cancer

Analysis of potential lung cancer biomarkers. Analysis of characteristic metabolite changes in lung cancer patients at different stages.

Metabolomics Analysis Process for Respiratory Diseases

Respiratory Diseases Metabolomics Service

Technology Platform for Metabolomics Analysis

Multiple analytical platforms, including GC-MS, LC-MS, UPLC-MS. Thousands of metabolites can be screened from a single biological sample, providing a comprehensive approach for probing disease mechanisms.

ChromatographyMass Spectrometry
GC (Q Exactive) (- mode MS)
HPLC: HILIC (+/- mode MS)
HPLC: RP C18 (+/-mode MS)
IC (- mode MS)
Q Exactive MS
Orbitrap Tribrid MS

Creative Proteomics is a well-established partner in biopharmaceutical research and has extensive experience in metabolomics analysis. We provide solutions for respiratory diseases research in the direction of metabolomics analysis, accelerating the exploration of new horizons in science. If you want to know more, please contact us. Looking forward to cooperating with you.

For Research Use Only. Not for use in diagnostic procedures.
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