Trait Biomarker Analysis Service

Metabolomics studies the types and amounts of endogenous metabolites in organisms and their patterns of change in response to internal and external factors.

Plant traits reflect the response and adaptation of plants to their growth environment, linking the environment, individual plant and ecosystem structure, processes and functions.  The elucidation of metabolites and metabolic pathways is important for the development of high-precision improved lines in crop breeding.

Complex traits in animals are the result of long-term adaptive evolution and are the main basis for the existence of animal diversity.  Metabolomics can be used to resolve complex animal traits and facilitate the assessment of breeding value for economic traits in livestock and poultry, diagnosis and prevention of diseases in agricultural animals, safety evaluation of livestock and poultry products, and use of animal medical models.

Creative Proteomics has established a high-throughput metabolomic analysis platform to provide trait biomarker analysis services to accelerate the discovery of metabolites and novel pathways of various biochemical types and to help improve the understanding of known existing pathways.

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Agricultural animal and plant trait marker analysis services can be applied to:

Agricultural plants

• Metabolomics quantitative trait locus: The analysis of natural variation in metabolic traits by quantitative trait loci helps to reveal the genetic basis controlling these variations and to resolve the genetic structure of metabolic trait formation. It is important to improve the quality and production performance of high-quality cultivars.
• Metabolic genome-wide association studies (mGWAS): Explain the natural genetic basis of different metabolic shifts in the plant metabolome.
• Metabolic analysis of tolerance to biological stress in crop plants: Study the metabolome associated with stress responses to reveal the molecules/metabolites that coordinate different plant susceptibility and/or resistance traits.
• Metabolites (or metabolic networks) were used to quantitatively characterize agricultural traits such as yield and quality.
• Analysis of heterozygosity markers
• Studies on root nodule symbiosis (RNS) in legumes: Nitrogen metabolism analysis
• Study on symbiotic nitrogen fixation in cereals and non-legume crops

Agricultural animals

• Characterization of differential traits in agricultural animals, molecular identification of metabolism of economically important traits
• Agricultural animal disease mechanism research
• Livestock and poultry meat flavor and animal products safety testing

Trait Biomarker Metabolome Analysis Process

Technology Platform for Metabolomics Analysis

Multiple analytical platforms, including GC-MS, LC-MS, UPLC-MS.

Creative Proteomics is a well-established partner in life science research and has extensive experience in metabolomics analysis. We provide solutions for trait biomarker in the direction of metabolomics analysis, accelerating the exploration of new horizons in science. If you want to know more, please contact us. Looking forward to cooperating with you.