Metabolomics Creative Proteomics

Newborns Metabolomics Service

The neonate's transition from fetal dependence on maternal metabolism to an independent individual completing his or her own metabolism is achieved through a series of metabolic transitions. The tremendous growth during the neonatal period is associated with specific alterations in metabolism, and its metabolic levels and metabolic patterns differ from those of children and adults at other stages of growth. It is due to this specificity in the early stages of life that understanding the metabolic characteristics of perinatal fetuses and neonates and their metabolic changes in disease states has new insights into the assessment of growth and development, disease states, and prognostic regression of neonates, and will provide a new basis for the selection of new treatment options and drug research.

Metabolomics is the process of detecting changes in the metabolic profile of the organism in disease states to find accurate and targeted metabolites that may translate into biomarkers of disease for these specific metabolites. Metabolites themselves are biologically active and exogenous key metabolites can reprogram metabolic pathways to adapt or inhibit metabolic changes in the body.

Creative Proteomics has established a platform for neonatal metabolomics analysis to help elucidate mechanisms of organismal response and reconstitution, providing a theoretical basis for disease prevention and treatment, and potential drug discovery.

Newborns Metabolomics Service

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Metabolomic analysis of perinatal growth and development studies

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Metabolomic analysis of inherited metabolic diseases

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Metabolomic analysis of neonatal sepsis

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Metabolomic analysis of neonatal necrotizing small bowel colitis

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Metabolomic analysis of bronchopulmonary dysplasia

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Metabolomic analysis of retinopathy of prematurity

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Metabolomic analysis of acute kidney injury in neonates

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Metabolomic analysis of neonatal asphyxia and HIE

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Metabolomic analysis of intraventricular hemorrhage in preterm infants

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Metabolomic analysis of bilirubin encephalopathy

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Metabolomic analysis of brain injury in preterm infants

Metabolomics Analysis Process for Newborns

Newborns Metabolomics Service

Technology Platform for Metabolomics Analysis

Multiple analytical platforms, including GC-MS, LC-MS, UPLC-MS. Thousands of metabolites can be screened from a single biological sample, providing a comprehensive approach for probing disease mechanisms.

ChromatographyMass Spectrometry
GC (Q Exactive) (- mode MS)
HPLC: HILIC (+/- mode MS)
HPLC: RP C18 (+/-mode MS)
IC (- mode MS)
Q Exactive MS
Orbitrap Tribrid MS

Creative Proteomics is a well-established partner in biopharmaceutical research and has extensive experience in metabolomics analysis. We provide solutions for newborns in the direction of metabolomics analysis, accelerating the exploration of new horizons in science. If you want to know more, please contact us. Looking forward to cooperating with you.

For Research Use Only. Not for use in diagnostic procedures.
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