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Metabolomics in Biomedical Research

Metabolomics in Biomedical Research

The analysis of metabolite composition (metabolome) and its change patterns is an important way to understand the molecular nature of life activity. The central task of metabolome analysis includes detecting, quantifying and mapping the dynamic patterns of changes in the biological metabolome, linking this pattern of change to the processes of biochemical reactions that occur.

Creative Proteomics has established a metabolomics research platform for biomedical research by combining NMR and chromatography-mass spectrometry techniques. We have developed and applied metabolomic analysis methods to study the metabolic basis of the development of important diseases and interventional regression.

The analysis of metabolomics data allows qualitative and quantitative analysis of small molecule metabolites in organisms and identification of the relative relationship between changes in metabolites and physiological and biochemical changes in organisms. Information on the pathogenesis of diseases, drug metabolism and pharmacological toxicity can be obtained by mining the information on the changes of metabolites in organisms during disease development and the metabolic changes in organisms caused by drug action.

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Solutions for
Biomedical Research

Liver Diseases

Cardiovascular Diseases

Respiratory Diseases

Oncology Research

Neurological Diseases

Kidney Diseases

Gastrointestinal Disease

Ophthalmology Diseases

Diabetes

Gout

Newborns

Aging

Postmortem

To study the metabolomic changes and mechanisms related to the development of important diseases and treatment prognosis.

To analyze the relationship between biochemical metabolism and disease, and to explore and reveal the etiology and pathological mechanisms of the disease from related metabolic abnormalities.

Exploring the mechanism of interaction between host metabolome and host organisms and its relationship with health.

Exploring the metabolomic response to stress on growth and development.

To provide precise guidance for new drug screening and development, study of drug mechanism of action, and drug toxicity evaluation.

Development of new methods for metabolome analysis combined with optimized chromatography-mass spectrometry

Metabolomics Solutions Analysis Strategies

Global Metabolomics

Untargeted metabolomics detection and bioinformatics methods are used to analyse the overall metabolic characteristics or changes of endogenous metabolites in disturbed organisms.