Carbohydrate Metabolism Analysis

Overview

Carbohydrate metabolites are one of major nutrients. They are found everywhere in living systems and play crucial roles in a wide variety of biological processes. Their best-known functions are as energy resources, as well as builders of structural bio-scaffoldings in animal cells and a backbone element in the RNA and DNA genetic molecules¹. However, their biological activities are more diverse. Carbohydrates are key players in cell signalling, molecular recognition, immunity and inflamation². Therefore, carbohydrates abnormal is closely associated to various pathologies like heart diseases and diabetes. Carbohydrate metabolism refers to as the various biochemical processes responsible for the formation, breakdown and interconversion of carbohydrates in living organisms. The carbohydrate metabolism provides a versatile tool to assess medical risks, identify novel biomarkers and gain insight to molecular mechanisms of disease by analysing hundreds of carbohydrate metabolites in individual’s samples. The carbohydrate metabolism analysis has been applied in a wide range of fields including biomarker discovery, human disease research, clinical diagnostics, drug discovery, food safety, nutrition and systems biology. With integrated array of separation, characterization, identification and quantification experience, Creative Proteomics provides reliable, rapid and cost-effective carbohydrate metabolism services for your various scientific purposes.

The Main Applications of Carbohydrate Metabolism Service

Biomarker discovery

Disease diagnostics

Drug discovery

Food safety

Metabolic disease research

Environmental health

Advantages of Our Carbohydrate Metabolism Service

Rich experience in different types of animal sample preparation

State of art facilities

Professional experiment design and data analysis

Competitive price

Short turnaround time

High accuracy, specificity, and sensitivity

Service Workflow

The carbohydrate metabolism service provided by Creative Proteomics is based on our cutting-edge chromatographic separation and mass spectrometry platforms. The experimental workflow involves 4 steps: sample collection, carbohydrates extraction, LS-MS data analysis and bioinformatics analysis (Figure 1). Our service will be tailored to specific samples and needs for optimal results.

Figure 1. The overall workflow of carbohydrate metabolism service.

List of Detectable Carbohydrate Metabolism at Creative Proteomics

Sample Requirements

We can analyze any biological materials including but not limited to cells and solid tissues from animals. If you need transport your samples to us, please follow the below requirements for different types of sample:

• Blood/plasma: 500ul/sample
• Urine: 1ml/sample
• Tissue: 200mg/sample
• Cells: 1x10⁷/sample
• Feces: 500mg/sample
• Shipment condition: dry ice

Report delivery

• Experimental procedures
• Instrument parameters of liquid chromatography and mass spectrometry
• MS raw data files and the summary of mass spectrometry data quality
• The identification/quantification of lipidic molecules data
• Bioinformatics analysis report (PCA, KEGG, etc.)

Equipped with advanced mass spectrometry for the determination of carbohydrate metabolites, powerful bioinformatic analysis software and a panel of experienced technicians and scientists, we provide customer-tailored animal targeted carbohydrate metabolomics analysis service with rapid experimental procedures and easy to read report, to advance your scientific research.

References

1. Khowala, S., Verma, D. & Banik, S. P. Carbohydrates. 2008, 1–93.
2. N.T. Porter, E.C. Martens. The critical roles of polysaccharides in gut microbial ecology and physiology. Annu Rev Microbiol. 2017, 71:349-369.