Galactose Metabolism Service

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Galactose is a kind of monosaccharide sugar, which can be got by hydrolysis of galactan. The metabolism of the galactose occurs almost entirely in the liver, and its metabolism include four major steps (Figure 1). The metabolism of the galactose provides other sugar intermediates that may be used for a wide range of metabolic processes. Therefore, galactose metabolism plays important roles in a variety of physiological and pathological conditions. It would not be surprising that galactose metabolism is important not only for fetal and neonatal development but also for adulthood1. The aberrant galactose metabolism contributes to various diseases like poor growth and feeding, jaundice and liver disease2. As a high-throughput tool, galactose metabolism analysis provides a powerful way to diagnosis and gain new insights in disease mechanism or treatment. With integrated array of separation, characterization, identification and quantification experience, Creative Proteomics provides reliable, rapid and cost-effective galactose metabolites analysis service for your various scientific purposes.

Figure 1. The overview of galactose metabolism.

The Main Applications of Galactose Metabolites Service

Biomarker discovery
Disease diagnostics
Drug discovery
Food safety
Metabolic disease research

Advantages of Our Galactose Metabolites Service

Rich experience in different types of animal sample preparation

State of art facilities

Professional experiment design and data analysis

Competitive price

Short turnaround time

High accuracy, specificity, and sensitivity

Service Workflow

The galactose metabolites service provided by Creative Proteomics is based on our cutting-edge chromatographic separation and mass spectrometry platforms. The experimental workflow involves 4 steps: sample collection, metabolites extraction, MS data analysis and bioinformatics analysis (Figure 1). Our service will be tailored to specific samples and needs for optimal results.

Figure 2. The overall workflow of galactose metabolism service.

List of Detectable Galactose Metabolites at Creative Proteomics

α-D-Galactose	Galactose 1-phosphate	UDP-galactose
UDP-glucose	Glycogen

Sample Requirements

We can analyze any biological materials including but not limited to cells and solid tissues from humans and animals, such as mice, rats, rabbits. If you need transport your samples to us, please follow the below requirements for different types of sample:

Blood/plasma: 500ul/sample
Urine: 1ml/sample
Tissue: 200mg/sample
Cells: 1x10⁷/sample
Feces: 500mg/sample
Shipment condition: dry ice

Report Delivery

Experimental procedures
Instrument parameters of liquid chromatography and mass spectrometry
MS raw data files and the summary of mass spectrometry data quality
The identification/quantification of lipidic molecules data
Bioinformatics analysis report (PCA, KEGG, etc.)

Equipped with advanced mass spectrometry for the determination of galactose metabolites, powerful bioinformatic analysis software and a panel of experienced technicians and scientists, we provide customer-tailored galactose metabolites analysis service with rapid experimental procedures and easy to read report, to advance your scientific research.

References

Ana I Coelho, Gerard T Berry, M Estela Rubio-Gozalbo. Curr Opin Clin Nutr Metab Care. 2015,18:422-427.
Berry, G. T. Disorders of Galactose Metabolism. 2015, Chapter 55.