Pentose and Glucuronate Interconversions Metabolism Service

Overview

Pentose and glucuronate interconversions are important carbohydrate metabolic pathway and involved in the interconversions of the monosaccharide pentose and glucuronate, the salts or esters of glucuronic acid. This pathway includes about 28 different members in human according to Kyoto Encyclopedia of Genes and Genomes database¹. Pentose and glucuronate interconversions pathway play an important role in many biosynthetic pathways like gluconeogenesis and transamination. deamination and lipogenesis. Therefore, aberrant pentose and glucuronate interconversions are associated with various diseases like familial tumoral calcinosis². As a high-throughput tool, pentose and glucuronate interconversions metabolites analysis provides a powerful way to diagnosis and gain new insights in disease mechanism or treatment. With integrated array of separation, characterization, identification and quantification experience, Creative Proteomics provides reliable, rapid and cost-effective pentose and glucuronate interconversions metabolites analysis service for your various scientific purposes.

The Main Applications of Pentose and Glucuronate Interconversions Metabolites Service

• Biomarker discovery
• Disease diagnostics
• Drug discovery
• Food safety
• Metabolic disease research

Advantages of Our Pentose and Glucuronate Interconversions Metabolites Service

Rich experience in different types of animal sample preparation

State of art facilities

Professional experiment design and data analysis

Competitive price

Short turnaround time

High accuracy, specificity, and sensitivity

Service Workflow

The pentose and glucuronate interconversions metabolites service provided by Creative Proteomics is based on our cutting-edge chromatographic separation and mass spectrometry platforms. The experimental workflow involves 4 steps: sample collection, metabolites extraction, MS data analysis and bioinformatics analysis (Figure 1). Our service will be tailored to specific samples and needs for optimal results.

Figure 1. The overall workflow of TCA cycle metabolism service.

List of Detectable Pentose and Glucuronate Interconversions Metabolites at Creative Proteomics

Sample Requirements

We can analyze any biological materials including but not limited to cells and solid tissues from humans and animals, such as mice, rats, rabbits. If you need transport your samples to us, please follow the below requirements for different types of sample:

• Blood/plasma: 500ul/sample
• Urine: 1ml/sample
• Tissue: 200mg/sample
• Cells: 1x10⁷/sample
• Feces: 500mg/sample
  Shipment condition: dry ice

Report Delivery

• Experimental procedures
• Instrument parameters of liquid chromatography and mass spectrometry
• MS raw data files and the summary of mass spectrometry data quality
• The identification/quantification of lipidic molecules data
• Bioinformatics analysis report (PCA, KEGG, etc.)

Equipped with advanced mass spectrometry for the determination of pentose and glucuronate interconversions, powerful bioinformatic analysis software and a panel of experienced technicians and scientists, we provide customer-tailored pentose and glucuronate interconversions metabolites analysis service with rapid experimental procedures and easy to read report, to advance your scientific research.

References

1. Minoru Kanehisa, Miho Furumichi. KEGG: new perspectives on genomes, pathways, diseases and drugs. Nucleic Acids Res. 2017,45:D353-D361.
2. Emily G Farrow, Erik A Imel, Kenneth E White. Miscellaneous non-inflammatory musculoskeletal conditions. Hyperphosphatemic familial tumoral calcinosis (FGF23, GALNT3 and αKlotho). Best Pract Res Clin Rheumatol. 2011, 25:735-747.