Creative Proteomics, as a leading biotechnology company, provides reliable, fast and cost-effective butanoate metabolism analysis service for animal related materials. We leverage our ample experience, professional expertise, and advanced technologies to speed up your scientific purposes of butanoate metabolism analysis in animal.
Butanoate is the conventional name for the conjugate base of butyric acid. The formula of the butyrate ion is C4H7O2. The name now is used as part of the name of esters and carboxylate salts of butyric acid. Endogenous butanoate is majorly produced from dietary fibres through bacterial fermentation in gut. Therefore, butanoate plays important roles in regulating colonic inflammation and gut immunological homeostasis. In addition, butanoate can influence on various physiological functions like increasing energy expenditure and reducing adiposity via its metabolites. It would not be surprising that aberrant butanoate metabolism is closely associated with different types of diseases including L-2-hydroxyglutaric aciduria and 3-Hydroxyacyl-CoA dehydrogenase deficiency. Understanding butanoate metabolism related metabolites will contribute to diagnosing these abnormal diseases and identifying potential targets for treatments. As a pioneer in carbohydrate metabolism, Creative Proteomics provides reliable, rapid and cost-effective butanoate metabolism analysis service to speed up diseases diagnosis and gain new insights in disease mechanism or treatment.
The Major Applications of Butanoate Metabolism Service
Discovering novel biomarkers of diseases
Improving diagnose diseases
Accelerating development of drugs
Gaining new mechanism of metabolic diseases
Advantages of Our Butanoate Metabolism Service
Rich experience in a variety of animal sample preparation
State of the art facilities
Professional experiment design and data analysis
Short experimental time
High accuracy, specificity, and sensitivity
Creative Proteomics provides butanoate metabolism service in a reliable and effective manner, based on our cutting-edge high-performance liquid chromatography (HPLC) platforms. The experimental procedures contain four major steps: sample collection, metabolites extraction, HPLC data analysis and bioinformatics analysis (Figure 1). Our service will be tailored to specific samples and needs for optimal results.
Figure 1. The overall workflow of butanoate metabolism service.
The potential Detectable Butanoate Metabolism related metabolites at Creative Proteomics
We can analyze a wide range of biological materials ranging from animal cells to animal solid tissues. If you need transport your samples to us, please follow the below requirements for different kinds of sample:
- Blood/plasma: 500ul/sample
- Urine: 1ml/sample
- Tissue: 200mg/sample
- Cells: 1x107/sample
- Feces: 500mg/sample
- Shipment condition: dry ice
- Experimental procedures
- Instrumental parameters of HPLC
- The raw data files of HPLC and the summary of HPLC data quality
- Bioinformatics analysis report
Equipped with advanced HPLC platforms for the determination of butanoate metabolism, professional bioinformatic analysis software and experienced technicians and scientists, Creative Proteomics provides customer-tailored butanoate metabolism analysis service with rapid experimental procedures and easy to read report, to accelerate your scientific research.
- Liu Hu, Wang Ji, He Ting, et al. Butyrate: A Double-Edged Sword for Health? Adv Nutr. 2018,9:21-29.
- Rzem Rim, Veiga-da-Cunha Maria, Noël Gaëtane, et al. A gene encoding a putative FAD-dependent L-2-hydroxyglutarate dehydrogenase is mutated in L-2-hydroxyglutaric aciduria. Proc Natl Acad Sci USA. 2004, 101:16849-16854.
- Yang Song-Yu, He Xue-Ying, Schulz Horst. 3-Hydroxyacyl-CoA dehydrogenase and short chain 3-hydroxyacyl-CoA dehydrogenase in human health and disease. FEBS J. 2005, 272:4874-4883.
For Research Use Only. Not for use in diagnostic procedures.