Creative Proteomics, as a leading biotechnology company, provides reliable, rapid and cost-effective amino sugar and nucleotide sugar metabolism analysis service in animal. We leverage our experience, expertise, and technologies to accelerate your scientific research of amino sugar and nucleotide sugar metabolism analysis in animal.
Amino sugars are chemical compounds that have a sugar backbone, in which one of the hydroxyl groups is replaced by an amine group. Glucosamine, galactosamine and neuraminic acid are three major types of amino sugars. In contrast, nucleotide sugars are the activated forms of monosaccharides. Nucleotide sugars act as glycosyl donors in glycosylation reactions via glycosyltransferases. Both amino sugars and nucleotide sugars play important roles in regulating protein function. It would not be surprising that aberrant amino sugar and nucleotide sugar metabolism links to various diseases like galactosemia and distal myopathy. As a high-throughput tool, amino sugar and nucleotide sugar metabolism analysis provides a powerful way to diagnosis and gain new insights in disease mechanism or treatment. With integrated array of separation, characterization, identification and quantification experience, Creative Proteomics provides reliable, rapid and cost-effective amino sugar and nucleotide sugar metabolism analysis service for your various scientific purposes.
The Main Applications of Amino Sugar and Nucleotide Sugar Metabolism Service
Metabolic disease research
Advantages of Our Amino Sugar and Nucleotide Sugar Metabolism Service
Rich experience in different types of animal sample preparation
State of art facilities
Professional experiment design and data analysis
Short turnaround time
High accuracy, specificity, and sensitivity
The amino sugar and nucleotide sugar metabolism service provided by Creative Proteomics is based on our cutting-edge high-performance liquid chromatography (HPLC) platforms. The experimental workflow involves 3 steps: sample collection, metabolites extraction, HPLC data analysis and bioinformatics analysis (Figure 1). Our service will be tailored to specific samples and needs for optimal results.
Figure 1. The overall workflow of amino sugar and nucleotide sugar metabolism service.
List of Detectable Amino Sugar and Nucleotide Sugar Metabolism at Creative Proteomics
|Uridine diphosphate glucose||Guanosine diphosphate mannose||Uridine diphosphate galactose|
|Uridine diphosphate glucuronic||Guanosine diphosphate fucose||Uridine diphosphate N-acetyl glucosamine|
|Uridine diphosphate N-acetyl galactosamine||Uridine diphosphate xylos||Cytidine monophosphate N-acetyl neuraminic acid|
We can analyze any biological materials including but not limited to cells and solid tissues from humans and animals, such as mice, rats, rabbits. If you need transport your samples to us, please follow the below requirements for different types of sample:
- Blood/plasma: 500ul/sample
- Urine: 1ml/sample
- Tissue: 200mg/sample
- Cells: 1x107/sample
- Feces: 500mg/sample
- Shipment condition: dry ice
- Experimental procedures
- Instrument parameters of liquid chromatography
- HPLC raw data files and the summary of HPLC data quality
- The identification/quantification of lipidic molecules data
- Bioinformatics analysis report (PCA, KEGG, etc.)
Equipped with advanced mass spectrometry for the determination of amino sugar and nucleotide sugar metabolism, powerful bioinformatic analysis software and a panel of experienced technicians and scientists, we provide customer-tailored amino sugar and nucleotide sugar metabolism analysis service with rapid experimental procedures and easy to read report, to advance your scientific research.
- Satu Mikkola. Nucleotide Sugars in Chemistry and Biology. Molecules, 2020, 25:5755.
- Kleta Robert, et al. Clinical, biochemical, and molecular diagnosis of a free sialic acid storage disease patient of moderate severity. Mol Genet Metab. 2004,82:137-143.
- Udd Bjarne. Genetics and pathogenesis of distal muscular dystrophies. Adv Exp Med Biol,2009,652:23-38.
For Research Use Only. Not for use in diagnostic procedures.