Metabolomics Creative Proteomics

Creative Proteomics Metabolomics

Alpha-Linolenic Acid Metabolism Service

Alpha-Linolenic Acid Metabolism Service

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Creative Proteomics is a pioneer in metabolism service and provides reliable, professional and cost-effective alpha-linolenic acid metabolism analysis service in animal. We leverage our rich experience, professional expertise, and advanced technologies to speed up your scientific purposes of alpha-linolenic acid metabolism analysis in animal.

Overview

Alpha-linolenic acid is a type of omega-3 fatty acid found in many common vegetable oils. Alpha-linolenic acid is one of two essential fatty acids, which animals have to ingest from diet, as the body requires them for tissue function but cannot synthesize them by themselves. Structurally, alpha-linolenic acid comprises an 18-carbon chain and three cis double bonds at positions 9, 12 and 15 from the methyl group. Functionally, alpha-linolenic acid is the substrate for the synthesis of longer-chain, more unsaturated n-3 fatty acids like eicosapentaenoic acid (20:5n-3) and docosahexaenoic acid (22:6n-3). Therefore, alpha-linolenic acid plays an important role in nutrition and health and its abnormal metabolism cause various human pathologies like cardiovascular disease and cancer. Scientists at Creative Proteomics take advantage of highly quantitative methods with high-performance liquid chromatography (HPLC) for the determination of alpha-linolenic acid levels in various samples. Furthermore, we provide reliable, rapid and cost-effective alpha-linolenic acid related service to speed up your research aims ranging from diseases diagnosis to gaining new insights in disease mechanism or treatment.

The Main Applications of Alpha-Linolenic Acid Metabolism Service

  • Identifying novel biomarkers of diseases
  • Improving diagnose diseases
  • Accelerating development of novel drugs
  • Gaining new mechanism of diseases

Advantages of Our Alpha-Linolenic Acid Metabolism Service

  • Constantly optimized protocol and analytical software
  • Professional experiment design
  • Quick turnaround time
  • High accuracy, specificity, and sensitivity

Service Workflow

Creative Proteomics provides alpha-linolenic acid metabolism analysis service in a reliable and effective manner, based on our cutting-edge HPLC platforms. The experimental procedures contain four main procedures: sample collection, metabolites extraction, HPLC data analysis and bioinformatics analysis (Figure 1). Our service will be tailored to specific samples and needs for optimal results.

The overall workflow of alpha-linolenic acid metabolismFigure 1. The overall workflow of alpha-linolenic acid metabolism

List of Partial Detectable Alpha-Linolenic Acid Metabolism Related Metabolites at Creative Proteomics

6,9,12,15,18,21-yetracosahexaenoic acidStearidonic acidEicosatetraeonic acidEicosapentaenoic acidDocosapentaenoic acid
9,12,15,18,21-tetracosapentaenoic acidAlpha-linolenic acidDocosahexaenoic acidTraumatic acidEtherolenic acid

Sample Requirements

We can analyze a wide range of biological materials including but not limited to cells and solid tissues from animals. If you need transport your samples to us, please follow the following requirements for different types of sample:

  • Blood/plasma: 500ul/sample
  • Urine: 1ml/sample
  • Tissue: 200mg/sample
  • Cells: 1x107/sample
  • Feces: 500mg/sample
    Shipment condition: dry ice

Report Delivery

  • Experimental protocols
  • Instrumental factors of HPLC
  • The raw data files of HPLC and the summary of HPLC data quality
  • Bioinformatics analysis report

Based on advanced HPLC platforms for the determination of alpha-linolenic acid metabolism, professional bioinformatic analysis software and experienced technicians and scientists, Creative Proteomics provides customer-tailored alpha-linolenic acid metabolism analysis service with rapid experimental procedures and easy to read report, to accelerate your scientific research.

References

  1. Koralek DO, Peters U, Andriole G, et al. A prospective study of dietary α-linolenic acid and the risk of prostate cancer (United States). Cancer Causes & Control. 2006.17: 783–791.
  2. Pan A, Chen M, Chowdhury R, et al. α-Linolenic acid and risk of cardiovascular disease: a systematic review and meta-analysis. Am. J. Clin. Nutr. 2012. 96: 1262–1273.
For Research Use Only. Not for use in diagnostic procedures.

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