Ecotoxicology Metabolomics Solutions
Submit Your InquiryEcotoxicology is centered on the study of the hazards and protection of non-human organisms (animals, plants, microorganisms) and their ecosystems by toxic and harmful factors, especially environmental pollutants, in order to protect the ecological environment. Metabolomics is able to observe early and/or sensitive responses to contamination. In ecotoxicological studies, the metabolome is able to link contaminant exposure of antecedent species to the early detection of hazards. Combined metabolomics and transcriptomics analysis can elucidate the pathways of adverse outcomes, thereby linking contamination damage to harmful outcomes in the species of interest.
Creative Proteomics offers metabolomics solutions for ecotoxicology studies based on high-resolution liquid chromatography and mass spectrometry technologies and advanced instrumentation. Metabolomics techniques are used to analyze a variety of endogenous biochemicals that may be affected by contaminants, to detect ultra-low limits of the contaminants themselves, and to analyze the environmental impact of toxic chemicals and their effects on biological organisms and their populations, communities, and terrestrial, freshwater, or marine ecosystems.
Metabolomics analysis services can be applied to ecotoxicology research:
- Elucidating the mechanism of action of pollutants
- Development of biomarkers in environmental biomonitoring
- Contaminant exposure and ecotoxicological evaluation
- Metabolic Response to Environmental Factor Stress: Real-time monitoring of altered physiological conditions and changes in metabolic profiles of organisms resulting from these environmental stressors.
- Measurement and monitoring of metabolite concentrations in physiological and disease states of many organisms, including mammalian and aquatic species
Types of Target Analytes That Can Be Analyzed
| Endogenous Metabolite Targets | Amino acids, Biogenic amines, Hexose, Acylcarnitine, Phosphatidylcholine, Sphingolipids, Bile acids, Fatty acids |
| Environmental Targets | Pesticides, Flame retardants, Bisphenol A, Polychlorinated biphenyls, Dioxins and furans, Fluorinated compounds, Chlorinated compounds, Pharmaceutical and personal care products, Polycyclic aromatic hydrocarbons, Naphthenic acids, Phthalates and their metabolites, Polybrominated diphenyl ethers, Parabens, Preservatives, Emerging contaminants |
| Substrate | Water, Cell tissue, Soil, Sediment, Sludge, Biofluid, Urine, Blood |
The Process for Metabolomics Analysis Services
Technology Platform for Metabolomics Analysis
Multiple analytical platforms, including GC-MS, LC-MS, UPLC-MS.
| Chromatography | Mass Spectrometry |
| GC (Q Exactive) (- mode MS) HPLC: HILIC (+/- mode MS) HPLC: RP C18 (+/-mode MS) IC (- mode MS) | Q Exactive MS Orbitrap Tribrid MS |
Creative Proteomics is a good partner in the environmental science field and has extensive experience in metabolomic analysis. We provide metabolomics solutions for ecotoxicology research to accelerate the exploration of new scientific horizons. If you would like to learn more, please contact us. We look forward to working with you.
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