Fucoxanthin (FX) is an oxygenated carotenoid widely found in algae, marine phytoplankton, aquatic shellfish and invertebrates.
Since its discovery, fucoxanthin has received much attention and has been used in clinical trials. It has become one of the hot spots for research and development because of its antioxidant, anti-cancer, anti-obesity and anti-diabetic biological activities and its good nutritional and health care values. Its effects on obesity and diabetes have been clinically proven, and it has been widely used in cosmetics and health food. Fucoxanthin can inhibit UV damage to epidermal mast cells, exert antioxidant activity, inhibit tyrosine kinase activity, and inhibit pigmentation, so it has been added to a variety of skin care products. Since fucoxanthin has a protective effect on the eyes, it is used to prevent or treat post-cataracts. Its ability to inhibit osteoclast differentiation and induce osteoclast apoptosis has led to its use in the prevention of osteoporosis and rheumatoid arthritis. When fucoxanthin is used in combination with adriamycin, it enhances the sensitivity of breast cancer cells to the drug and has the potential to be an adjuvant to adriamycin chemotherapy regimens in breast cancer treatment.
Creative Proteomics can provide you with qualitative and quantitative analysis of rockweed xanthan based on LC-MS/MS and GC-MS analytical platforms.
Structure of fucoxanthin
Waters ACQUITY UPLC, MS-SCIEX QTRAP 4500/5500/6500
Agilent 7890B-5977A, Thermo TRACE 1300-TSQ 9000
Technical Workflow of Targeted Metabolomics of Fucoxanthin
- Standard curve creation
- Raw data preprocessing
- Absolute quantitation of fucoxanthin
Sample Preparation Suggestions
|Sample type||Suggested sample quantity (per case)||Number of repetitions (recommended)|
|Algae samples||≥ 30mg freeze-dried powder / 300mg fresh samples||≥ 6|
|Plant tissues||≥ 1g||≥ 6|
|Animal and clinical tissues||≥ 200 mg||≥ 10|
|Serum, plasma||≥ 500 μl||≥ 6|
|Urine||≥ 200 μl||≥ 6|
|Stool, intestinal contents||≥ 0.5 g||≥ 6|
|Cell||≥ 107||≥ 6|
※ There is no restriction on sample varieties. For varieties with special requirements or rare varieties, please contact us for more information.
After collecting the samples, they were quickly frozen in liquid nitrogen, and then transferred to -80°C for storage. Transported on dry ice.
Feedback to Customers
- A detailed technical report will be provided at the end of the entire project, including experimental procedures and instrument parameters.
- The report also includes quantitative results of targeted metabolites.
- Part of the mass spectrum picture
- Raw data
- A standard experimental procedure takes about 1 ~ 4 weeks.
Creative Proteomics has an integrated separation, detection, identification and quantification system, with excellent robustness and reproducibility, high sensitivity and ultra-sensitivity, and can provide fast and reliable targeted metabolomics services. Our one-stop service model can help you achieve a seamless connection between upstream and downstream experiments. Coupled with personalized analysis services, your analysis can reach the final research purpose. If you have any questions or specific requirements, please feel free to contact us.
For Research Use Only. Not for use in diagnostic procedures.