Glucose Analysis Service

What is Glucose?

Glucose is a monosaccharide that is the main source of energy for living organisms. It is an important carbohydrate that is vital to many biological functions. It circulates in the bloodstream and is the basic energy substrate for cells. In addition to providing energy, glucose serves as a precursor for the creation of other macromolecules such as lipids, nucleotides and glycogen, the stored form of glucose in mammals. To produce ATP (adenosine triphosphate), it participates in a number of metabolic pathways, including glycolysis, gluconeogenesis and the citric acid cycle.

Our Glucose Analysis Services Can be Used in The Following Areas:

Metabolism Study

Glucose is a key molecule that participates in various metabolic pathways in living organisms. Glucose quantitative analysis assists researchers in learning about energy metabolism, carbohydrate metabolism, and the interactions between glucose and other metabolites. Understanding the various principles of glucose metabolism allows you to decipher the intricacies of metabolic illnesses like diabetes and discover viable therapeutic strategies.

Drug Discovery and Development

In the process of finding and developing new drugs, glucose measurement is extremely important. It helps assess how pharmaceutical substances affect glucose metabolism and identifies possible therapeutic candidates that target certain metabolic pathways. Researchers may evaluate how medications affect glucose uptake, utilization, and regulation via glucose analysis, which enables the creation of brand-new treatments for metabolic illnesses.

Nutritional Studies

Quantitative analysis of glucose allows you to assess the impact of different diets on glucose metabolic responses and overall metabolic health.

Biochemical Pathway Investigations

You can examine glucose conversion to other metabolites such as glycogen, lactate, or lipids by assessing glucose levels. This information contributes to a better understanding of the links between various metabolic pathways and the role of glucose in cellular processes such as biosynthesis, energy storage, and signal transmission.

Environmental and Industrial Applications

In environmental studies, glucose analysis can be used to assess organic matter degradation rates, microbial activity, and carbon cycling in ecosystems. In the industrial sector, glucose analysis aids in the production of various biofuels, fermentation processes, and the optimization of microbial bioproduction platforms.

Molecular structure of glucose

Technical Route of Glucose Analysis

At Creative Proteomics, we are proud to offer comprehensive glucose qualitative and quantitative analysis services utilizing liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) technology. LC-MS/MS is a powerful analytical technique that combines the separation capabilities of liquid chromatography with the sensitivity and specificity of mass spectrometry. It involves the separation of analytes by liquid chromatography, followed by their ionization, fragmentation, and detection using multiple mass analyzers.

Sample Types of Glucose Assay

We have expertise in analyzing various sample types for glucose content. These include but are not limited to:

Biological samples:

• Blood plasma/serum
• Urine
• Tissue homogenates
• Cell culture supernatants

Food and beverage samples

Feedback to Customers

Creative Proteomics will provide you with detailed technical reports, including

• Experimental steps
• Related mass spectrometry parameters
• Part of the mass spectrum picture
• Raw data
• Metabolic molecular identification results

Creative Proteomics offers several approaches to metabolomics studies, delivers precise and detailed data and analysis report. We can also customize the methods or establish new methods together with our collaborators, so they are fit-for-purpose and meet your specific needs. If you have any questions or specific requirements, please feel free to contact us.

References

1. Riera-Borrull M, Rodríguez-Gallego E, Hernández-Aguilera A, et al. Exploring the process of energy generation in pathophysiology by targeted metabolomics: performance of a simple and quantitative method. Journal of the American Society for Mass Spectrometry, 2015, 27(1): 168-177.
2. Kim M J, Lee M Y, Shon J C, et al. Untargeted and targeted metabolomics analyses of blackberries – Understanding postharvest red drupelet disorder. Food Chemistry, 2019, 300:125169.
3. Wang X, Zhao X, Zhao J, et al. Serum metabolite signatures of epithelial ovarian cancer based on targeted metabolomics. Clinica Chimica Acta, 2021, 518: 59-69.